Stuart B Goodman Selected Research

Polyethylene (Polythene)

10/2021	Suppression of NF-κB-induced chronic inflammation mitigates inflammatory osteolysis in the murine continuous polyethylene particle infusion model.
1/2021	Different Effects of Intramedullary Injection of Mesenchymal Stem Cells During the Acute vs. Chronic Inflammatory Phase on Bone Healing in the Murine Continuous Polyethylene Particle Infusion Model.
1/2021	Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover.
1/2017	The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction.
1/2016	The Role of Macrophages in the Biological Reaction to Wear Debris from Artificial Joints.
1/2016	Hip arthroplasty for treatment of advanced osteonecrosis: comprehensive review of implant options, outcomes and complications.
3/2015	NF-κB decoy oligodeoxynucleotide enhanced osteogenesis in mesenchymal stem cells exposed to polyethylene particle.
7/2014	Current modes of failure in TKA: infection, instability, and stiffness predominate.
7/2014	Polyethylene wear and osteolysis is associated with high revision rate of a small sized porous coated THA in patients with hip dysplasia.
2/2014	High complication rate in revision total hip arthroplasty in juvenile idiopathic arthritis.

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Stuart B Goodman Research Topics

Disease

62	Osteolysis 10/2021 - 09/2003
43	Inflammation (Inflammations) 10/2021 - 09/2003
27	Infections 04/2021 - 06/2003
26	Osteonecrosis (Kienbock's Disease) 01/2022 - 01/2009
18	Pain (Aches) 05/2022 - 04/2005
17	Arthritis (Polyarthritis) 01/2022 - 10/2006
13	Osteoarthritis 10/2020 - 01/2005
10	Wounds and Injuries (Trauma) 01/2022 - 08/2004
7	Bone Resorption 04/2022 - 10/2002
7	Neoplasms (Cancer) 12/2018 - 08/2004
7	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 02/2014 - 01/2005
5	Obesity 11/2019 - 01/2016
5	Foreign Bodies (Foreign Body) 06/2019 - 01/2005
4	Disease Progression 01/2021 - 12/2018
4	Postoperative Pain 06/2017 - 09/2010
4	Foreign-Body Reaction 01/2017 - 07/2010
4	Rheumatoid Arthritis 01/2014 - 10/2006
3	Knee Osteoarthritis 01/2022 - 12/2011
3	Cardiac Arrhythmias (Arrythmia) 10/2021 - 11/2019
3	Alcoholism (Alcohol Abuse) 01/2021 - 01/2018
3	Substance-Related Disorders (Drug Abuse) 12/2015 - 09/2012
3	Hip Dislocation 07/2014 - 06/2006
3	Periprosthetic Fractures 06/2014 - 09/2010
2	Atrial Fibrillation 10/2021 - 11/2019
2	Leukemia 06/2021 - 10/2006
2	Hematologic Neoplasms (Hematological Malignancy) 10/2020 - 01/2020
2	Hemorrhage 09/2020 - 09/2017
2	Venous Thromboembolism 09/2020 - 09/2017
2	Chronic Pain 01/2020 - 10/2017
2	Osteoporosis 01/2020 - 08/2007
2	Anemia 01/2020 - 09/2017
2	Synovitis 02/2018 - 05/2011
2	Weight Gain 10/2017 - 01/2017
2	Congenital Abnormalities (Deformity) 02/2016 - 04/2005
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 12/2015 - 01/2015
2	Medically Unexplained Symptoms 01/2015 - 06/2014
2	AIDS-Related Complex (ARC) 10/2010 - 10/2007
1	Joint Diseases (Joint Disease) 01/2022

Drug/Important Bio-Agent (IBA)

22	Polyethylene (Polythene)IBA 10/2021 - 06/2006
19	Biological ProductsIBA 10/2020 - 01/2005
15	CytokinesIBA 01/2021 - 10/2002
11	Biocompatible Materials (Biomaterials)IBA 04/2022 - 09/2003
11	Interleukin-4 (Interleukin 4)IBA 01/2021 - 07/2012
10	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2021 - 08/2007
7	Opioid Analgesics (Opioids)IBA 05/2022 - 09/2012
7	Proteins (Proteins, Gene)FDA Link 06/2019 - 01/2011
7	ultra-high molecular weight polyethylene (UHMWPE)IBA 03/2015 - 09/2010
6	artemisinin-naphthoquine combinationIBA 06/2021 - 01/2019
5	SteroidsIBA 01/2021 - 01/2018
5	ChemokinesIBA 12/2019 - 04/2012
4	LigandsIBA 01/2022 - 05/2011
4	TitaniumIBA 05/2021 - 11/2004
4	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2019 - 01/2014
4	Transcription Factors (Transcription Factor)IBA 01/2019 - 08/2014
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 11/2019
3	CollagenIBA 01/2022 - 02/2015
3	Anti-Bacterial Agents (Antibiotics)IBA 04/2021 - 01/2016
3	MetalsIBA 04/2021 - 01/2015
3	Toll-Like Receptors (Toll-Like Receptor)IBA 07/2017 - 05/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 09/2003
2	SolutionsIBA 01/2022 - 06/2014
2	Diphosphonates (Bisphosphonates)IBA 01/2022 - 08/2007
2	InterleukinsIBA 01/2021 - 01/2017
2	Becaplermin (PDGF-BB)FDA Link 01/2021 - 01/2021
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 09/2020 - 09/2017
2	Enoxaparin (Lovenox)FDA LinkGeneric 09/2020 - 09/2017
2	Factor Xa InhibitorsIBA 09/2020 - 09/2017
2	Warfarin (Coumadin)FDA LinkGeneric 09/2020 - 09/2017
2	InflammasomesIBA 01/2020 - 02/2016
2	GlucocorticoidsIBA 01/2019 - 08/2007
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2018 - 01/2015
2	MicroRNAs (MicroRNA)IBA 01/2018 - 10/2017
2	Polymethyl Methacrylate (Sol)IBA 01/2017 - 08/2011
2	3,5-tetrahydroaldosterone sulfate (THAS)IBA 03/2016 - 07/2014
2	Carboxypeptidase BIBA 09/2011 - 10/2009
2	Interleukin-1 (Interleukin 1)IBA 05/2005 - 05/2004
1	Analgesics (Analgesic Drugs)IBA 05/2022
1	Denosumab FDA Link 01/2022
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2022
1	Hyaluronic Acid (Hyaluronan)IBA 01/2022
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2022
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2022

Therapy/Procedure

38	Replacement Arthroplasty 01/2022 - 06/2003
27	Arthroplasty 01/2022 - 06/2003
25	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2021 - 09/2003
21	Knee Replacement Arthroplasty (Total Knee Replacement) 05/2022 - 06/2003
11	Therapeutics 01/2022 - 08/2010
11	Decompression 01/2022 - 01/2018
8	Reoperation 01/2020 - 01/2013
6	Operative Surgical Procedures 01/2018 - 11/2013
6	Prostheses and Implants (Prosthesis) 10/2017 - 11/2004
4	Debridement 04/2021 - 03/2012
4	Immunomodulation 01/2021 - 12/2017
4	Bone-Implant Interface 01/2016 - 01/2011
2	Replantation 10/2018 - 01/2016
2	Catheters 11/2017 - 06/2017
2	Arthrodesis 10/2017 - 10/2010
2	Surgical Amputation (Amputations) 10/2016 - 01/2014
2	Surgical Navigation Systems 10/2007 - 08/2006
1	Extracorporeal Shockwave Therapy 01/2022